Author’s response to reviews Title: Acacia hydaspica R. Parker Prevents Doxorubicin-Induced Cardiac Injury by Attenuation of Oxidative Stress and Structural Cardiomyocyte Alterations in rats Authors:
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Title: Acacia hydaspica R. Parker Prevents Doxorubicin-Induced Cardiac Injury by Attenuation of Oxidative Stress and Structural Cardiomyocyte Alterations in rats Authors: Tayyaba Afsar ([email protected]) Suhail Razak ([email protected]) Khalid Batoo ([email protected]) Muhammad Khan ([email protected]) Version: 1 Date: 05 May 2017 Author’s response to reviews: To Dear editor BMC Complementary and Alternative medicine I am pleased to submit revise version of original article entitled “Acacia hydaspica R. Parker Prevents Doxorubicin-Induced Cardiac Injury by Abrogation of Oxidative Stress and Structural Cardiomyocyte Alterations in rats; A Randomized Controlled trial” in the Journal of BMC Complementary and Alternative medicine. Response The table summarizing the total phenolic content, total flavonoid content, HPLC detected components and isolated compounds with citations from previous reports has been included according to editor’s suggestion.
منابع مشابه
Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats
BACKGROUND The use of doxorubicin (DOX) an anthracycline antineoplastic agent is withdrawn due to its cardio-toxic side effects. Oxidative stress has been recognized as the primary cause of DOX induced cardiotoxicity. We have investigated whether polyphenol rich ethyl acetate extract of Acacia hydaspica (AHE) can attenuate doxorubicin-induced cardiotoxicity via inhibition of oxidative stress. ...
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BACKGROUND Cisplatin (CP) drug is platinum compounds used for the treatment of various human malignancies. However, adverse outcomes related to CP restrict its usage. Acacia hydaspica is a natural shrub with various pharmacological properties. The current investigation aimed to assess the protective potential of A. hydaspica polyphenol rich ethyl acetate extract (AHE) against cisplatin (CP) ind...
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BACKGROUND Cisplatin (CP) is recommended as a first-line chemotherapeutic agent for solid tumors, however its usage outcomes in severe adverse effects. Acacia hydaspica possesses various phytochemicals and pharmacological activities. The current study aimed to investigate the protective effect of A. hydaspica ethyl acetate extract (AHE) against CP induced aberrations in lipid profile and hepato...
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تاریخ انتشار 2017